丝裂原活化蛋白激酶激酶2抗体-抗体-抗体-生物在线
丝裂原活化蛋白激酶激酶2抗体

丝裂原活化蛋白激酶激酶2抗体

商家询价

产品名称: 丝裂原活化蛋白激酶激酶2抗体

英文名称: P44 MAPK(ERK1) Antibody

产品编号: ICP9810

产品价格: null

产品产地: 进口

品牌商标: 进口

更新时间: null

使用范围:

上海研卉生物科技有限公司
  • 联系人 :
  • 地址 : 上海市嘉定区叶城路1288号
  • 邮编 :
  • 所在区域 : 上海
  • 电话 : 187****6455
  • 传真 : 021-69000211
  • 邮箱 : yanhuibio@163.com

Product Description: Affinity purified rabbit polyclonal anti-p44 MAPK antibody is developed with c-terminal peptide of human MAPK (ERK1).
 
Species: Bovine

Formulation: 250 µg/mL in TBS, 50% Glycerol, 0.01% NaN3.

Storage & Stability: Store product at –20℃. Three years from date of shipping

Immunogen: Human p44 ERK1 c-terminal peptide-KLH conjugate

Purification: The antibody is affinity purified with p44 ERK1 c-terminal peptide-on agarose

Specificity: The antibody is recognizes p44 ERK1 of human, rat, bovine, mouse, and rabbit. There is slight cross-reaction with p42 ERK2

Applications: ELISA, WB, IP

Scientific Description:  One of the members of mitogen-activated protein kinases is called p44 MAP Kinase (Erk1). It participates in cell growth and differentiation. [1,2] By phosphorylating the transcription factors (e., ELK-1), p44 MAP kinase (Erk1) regulates meiosis as well as mitosis of the cell. In the case of human MAP kinase, Erk1 activates Elk-1 through phosphorylation of threonine 202 and tyrosine 204. It is also known that Erk1 autophosphorylates tyrosine. [3]

References: 1. Charest, D.L, et al. Mol Cell Biol. 1993, 13, 4679–4690. 2. Marshall, C.J. Cell 1995, 80, 179–185.
3. Payne, D.M., et al. EMBO J. 1991, 10, 885–892.
 
 
 
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